Annual report pursuant to Section 13 and 15(d)

Fair Value Measurements - Warrant Liabilities And Convertible Notes At Fair Value (Detail)

v3.19.1
Fair Value Measurements - Warrant Liabilities And Convertible Notes At Fair Value (Detail)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Expected dividend yield   0.00%
Helocyte [Member] | Convertible Debt [Member] | Measurement Input, Expected Dividend Rate [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Expected dividend yield 0.00%
Helocyte [Member] | Convertible Debt [Member] | Measurement Input, Price Volatility [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Expected volatility   52.40%
Helocyte [Member] | Minimum [Member] | Convertible Debt [Member] | Measurement Input, Risk Free Interest Rate [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Risk-free interest rate   1.53%
Helocyte [Member] | Minimum [Member] | Convertible Debt [Member] | Measurement Input, Expected Term [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Expected term in years   6 months
Helocyte [Member] | Maximum [Member] | Convertible Debt [Member] | Measurement Input, Risk Free Interest Rate [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Risk-free interest rate   1.72%
Helocyte [Member] | Maximum [Member] | Convertible Debt [Member] | Measurement Input, Expected Term [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Expected term in years   10 months 28 days
Caelum Convertible Notes [Member] | Convertible Debt [Member] | Measurement Input, Risk Free Interest Rate [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Risk-free interest rate 2.302%  
Caelum Convertible Notes [Member] | Convertible Debt [Member] | Measurement Input, Expected Dividend Rate [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Expected dividend yield 0.00%
Caelum Convertible Notes [Member] | Convertible Debt [Member] | Measurement Input, Expected Term [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Expected term in years 3 months 25 days  
Caelum Convertible Notes [Member] | Convertible Debt [Member] | Measurement Input, Price Volatility [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Expected volatility 67.00% 70.00%
Caelum Convertible Notes [Member] | Minimum [Member] | Convertible Debt [Member] | Measurement Input, Risk Free Interest Rate [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Risk-free interest rate   1.506%
Caelum Convertible Notes [Member] | Minimum [Member] | Convertible Debt [Member] | Measurement Input, Expected Term [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Expected term in years   5 months 16 days
Caelum Convertible Notes [Member] | Maximum [Member] | Convertible Debt [Member] | Measurement Input, Risk Free Interest Rate [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Risk-free interest rate   1.851%
Caelum Convertible Notes [Member] | Maximum [Member] | Convertible Debt [Member] | Measurement Input, Expected Term [Member]    
Fair Value Measurement Inputs and Valuation Techniques [Line Items]    
Expected term in years   1 year 8 months 12 days