Annual report pursuant to Section 13 and 15(d)

Fair Value Measurements - Changes in Fair Value of Financial Instruments (Detail)

v3.6.0.2
Fair Value Measurements - Changes in Fair Value of Financial Instruments (Detail) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]    
Balance $ 2,599 $ 4,160
Additions during the period 19,089 289
Issuance of warrants (793) (613)
Change in fair value of investment (1,071) (1,675)
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings 78  
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Derivative Liability Gain Loss Included In Earnings 1,039 438
Balance 20,942 2,599
Contingently Issuable Warrant [Member]    
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]    
Balance 114 0
Additions during the period 14,040 175
Issuance of warrants (793) (613)
Change in fair value of investment 0 0
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings 0  
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Derivative Liability Gain Loss Included In Earnings 1,300 438
Balance 14,661 114
Helocyte Convertible Note At Fair Value [Member]    
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]    
Balance 0  
Additions during the period 4,409  
Issuance of warrants 0  
Change in fair value of investment 0  
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings 78  
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Derivative Liability Gain Loss Included In Earnings 0  
Balance 4,487 0
Avenue Convertible Note, at fair value [Member]    
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]    
Balance 0  
Additions during the period 200  
Issuance of warrants 0  
Change in fair value of investment 0  
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings  
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Derivative Liability Gain Loss Included In Earnings  
Balance 200 0
Warrant liabilities [Member]    
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]    
Balance 0 0
Additions during the period 440 114
Issuance of warrants 0
Change in fair value of investment 0 0
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings 0  
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Derivative Liability Gain Loss Included In Earnings (261) 0
Balance 179 0
Investment In Laser Device [Member]    
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]    
Balance 250 250
Additions during the period 0 0
Issuance of warrants 0
Change in fair value of investment 0 0
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings 0  
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Derivative Liability Gain Loss Included In Earnings 0 0
Balance 250 250
Investment In Origo [Member]    
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]    
Balance 2,235 3,910
Additions during the period 0 0
Issuance of warrants 0
Change in fair value of investment (1,071) (1,675)
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings 0  
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Derivative Liability Gain Loss Included In Earnings 0 0
Balance $ 1,164 $ 2,235