Annual report pursuant to Section 13 and 15(d)

Segment Information - Operating Results by Reportable Segment (Detail)

v3.8.0.1
Segment Information - Operating Results by Reportable Segment (Detail) - USD ($)
$ in Thousands
 3 Months Ended 12 Months Ended
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Segment Reporting Information [Line Items]                      
Net Revenue                 $ 187,584 $ 16,480 $ 863
Direct cost of goods                 (3,658) (790) 0
Sales and marketing costs                 (10,410) (5,774) (2,850)
Research and development                 (52,486) (35,134) (29,810)
General and administrative                 (40,487) (28,229) (18,734)
National expenses                 288,792 82,190 51,394
Segment loss from operations $ (73,154) $ (79,489) $ (73,890) $ (62,259) $ (32,217) $ (17,180) $ (17,042) $ (15,571) (101,208) (65,710) (50,531)
Segment assets 245,950       170,731       245,950 170,731 118,610
Dermatology Products Sales [Member]                      
Segment Reporting Information [Line Items]                      
Net Revenue                 15,520 3,587 273
Direct cost of goods                 (3,658) (790) 0
Sales and marketing costs                 (10,410) (5,774) (2,850)
Research and development                 0 0 0
General and administrative                 (1,140) (1,474) (1,682)
National expenses                 0  
Segment loss from operations                 312 (4,451) (4,259)
Segment assets 9,644       4,469       9,644 4,469 1,965
Pharmaceutical And Biotechnology Product Development [Member]                      
Segment Reporting Information [Line Items]                      
Net Revenue                 1,725 2,570 590
Direct cost of goods                 0 0 0
Sales and marketing costs                 0 0 0
Research and development                 (52,486) (35,134) (29,810)
General and administrative                 (39,347) (26,755) (17,052)
National expenses                 0  
Segment loss from operations                 (90,108) (59,319) (46,272)
Segment assets 187,941       115,145       187,941 115,145 116,542
National [Member]                      
Segment Reporting Information [Line Items]                      
National expenses                   (12,263)  
Consolidated [Member]                      
Segment Reporting Information [Line Items]                      
National expenses                   (12,263)  
Financial Service Activities [Member]                      
Segment Reporting Information [Line Items]                      
Net Revenue                 170,339 10,323 0
Direct cost of goods                 0 0 0
Sales and marketing costs                 0 0 0
Research and development                 0 0 0
General and administrative                 0 0 0
National expenses                 (181,751)    
Segment loss from operations                 (11,412) (1,940) 0
Segment assets $ 48,365       $ 51,117       $ 48,365 $ 51,117 $ 0