Annual report pursuant to Section 13 and 15(d)

Stockholders' Equity - Additional Information (Detail)

v3.8.0.1
Stockholders' Equity - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Jul. 15, 2015
Jun. 01, 2015
Dec. 01, 2017
Nov. 30, 2017
Nov. 30, 2017
Oct. 31, 2017
Jun. 26, 2017
Jun. 01, 2017
Jan. 31, 2017
Dec. 31, 2016
Jun. 01, 2016
May 31, 2016
Feb. 23, 2016
Jan. 31, 2016
Jan. 02, 2016
Dec. 02, 2015
Oct. 30, 2015
Sep. 18, 2015
Jun. 30, 2013
Dec. 31, 2016
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Dec. 15, 2017
Oct. 26, 2017
Jun. 02, 2015
Mar. 17, 2014
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Stock Based compensation, authorized number of shares                                               12,506,679            
Employee Stock Purchase Plan to eligible employees, Reckoning fair value percentage during offering period     85.00%         85.00%                               85.00%            
Employee Stock Purchase Plan to eligible employees, compensation expense recognized                                               $ 200,000 $ 0.1 $ 45,000        
Common Stock issued in connection with the first ESPP offering     45,657         22,076                                            
Share Based Compensation Restricted Stock Units                                               $ 11,300,000 $ 9,900,000 6,900,000        
Common Stock Par Or Stated Value Per Share     $ 3.26         $ 1.90   $ 0.001                   $ 0.001       $ 0.001 $ 0.001          
Share Price     $ 3.83         $ 2.24                                            
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized                                               12,506,679            
Proceeds from Stock Options Exercised                                               $ 27,000 $ 0 216,000        
Class of Warrant or Right, Exercise Price of Warrants or Rights             $ 4.02                     $ 7.00           $ 2,500            
Stock Issued During Period, Shares, Issued for Services                         10,000                                  
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                                               7.00            
Proceeds from issuance of Common stock             $ 34,200,000                                              
Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized                                               7,700,000            
Share-based Compensation                                               $ 14,005,000 12,128,000 14,291,000        
Net Proceeds From Issuance Of Warrants                                               $ 51,500,000            
Stock Issued For Exercise Of Warrants                                               10,000            
Warrant Purchase Price Per Unit                                               $ 50,000            
Common Stock, Capital Shares Reserved for Future Issuance                                               125,000            
Stock Issued During Period Shares warrants Exercised                                   2,500                        
Stock Issued During Period, Shares, New Issues           43,292                       10,000                        
Stock Issued During Period, Value of Warrants Excercised                                   $ 50,000                        
Equity Method Investment, Ownership Percentage                                                           35.00%
Warrants Issued                                 139,592                          
Stock Issued During Period, Value, New Issues                                                 53,000,000          
Payments of Stock Issuance Costs                                               $ 2,804,000 0 0        
Adjustments To Additional Paid In Capital At Market Offering Costs                                                 $ (79,000)          
Preferred Stock Shares Outstanding                   0                   0       1,000,000 0          
Preferred Stock Shares Authorized                   15,000,000                   15,000,000       15,000,000 15,000,000          
Preferred Stock, Value, Issued                   $ 0                   $ 0       $ 1,000 $ 0          
Preferred Stock Shares Issued                   0                   0       1,000,000 0          
Dividends, Preferred Stock                                               $ 299,000            
Proceeds from Issuance of Preferred Stock and Preference Stock                                               $ 25,000,000 $ 0 $ 0        
Payments for Other Fees       $ 2,700,000 $ 100,000                                 $ 1,265,000                
Proceeds from Fees Received                                           14,420,000 $ 1,265,000              
Percentage of Placement of Agent Fee                                   10.00%           10.00%            
Common Stock Shares Outstanding                   48,932,023                   48,932,023       50,991,285 48,932,023          
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized                                               $ 0            
Employee Service Share Based Compensation Vested Awards Total Compensation Cost Not Yet Recognized                                               0            
Common Stock Value             800,000     $ 49,000                   $ 49,000       $ 51,000 $ 49,000          
Payments for Fees       $ 2,700,000 $ 100,000                                 $ 1,265,000                
Market Offering [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Shares Issued, Price Per Share                       $ 2.89                                    
Proceeds from issuance of Common stock                       $ 400,000                                    
Issuance of Common Stock for At the Market Offering in shares                       150,556                                    
Adjustments To Additional Paid In Capital At Market Offering Costs                       $ 79,000                                    
IPO [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Fees and Commissions             $ 2,300,000                                              
Plan 2013 [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Stock Based compensation, authorized number of shares                                               10,000,000            
Stock Based compensation, shares available for issuance                                               3,493,321            
Employee Stock Purchase Plan to eligible employees, compensation expense recognized                                               $ 2,300,000,000,000            
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized                                               10,000,000            
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant                                               3,493,321            
Plan 2007 [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Stock Based compensation, authorized number of shares                   1,500,000                   1,500,000       6,000,000 1,500,000          
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized                   1,500,000                   1,500,000       6,000,000 1,500,000          
Longterm Incentive Program [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested in Period, Fair Value                                               $ 1,500,000 $ 1,400,000          
Class of Warrant or Right, Outstanding 500,000                                                          
Weighted Market Value Percentage of Invested Capital 44.80%                                                          
Weighted Average Cost Percentage of Capital 30.00%                                                          
Stock Issued During Period, Shares, Issued for Services                                               500,000            
Capital Units, Authorized                                               100,000,000            
Share-based Compensation                                               $ 600,000 300,000          
Sharebased Compensation Arrangement By Sharebased Payment Award Percentage Of Shares Granted                             1.00%                              
Noncontrolling Interest, Ownership Percentage by Noncontrolling Owners                                               5.00%            
Plan 2017 and 2013 [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Stock Based compensation, shares available for issuance                                                   16,000,000        
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant                                                   16,000,000        
Series A Preferred Stock [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Shares Issued, Price Per Share       $ 25.0 $ 25.0                                                  
Stock Issued During Period, Value, New Issues       $ 25,000,000                                                    
Adjustments To Additional Paid In Capital At Market Offering Costs                                                 $ 0          
Preferred Stock Shares Outstanding                   0                   0         0          
Preferred Stock Shares Authorized                                                       5,000,000    
Preferred Stock, Value, Issued                                                     $ 25,000,000      
Preferred Stock Shares Issued                   0                   0         0   1,000,000      
Preferred Stock, Dividend Rate, Percentage       9.375%                                       9.375%            
Dividends Payable, Amount Per Share                                               $ 0.299479     $ 2.34375      
Dividends, Preferred Stock                                               $ 0            
Preferred Stock, Liquidation Preference Per Share                                               $ 25.00            
Proceeds from Issuance of Preferred Stock and Preference Stock       $ 22,200,000                                                    
After Amendment [Member] | Convertible Preferred Stock [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Share Price                                               $ 0.001            
Capital Units, Authorized                                               100,000,000            
Checkpoint [Member] | Private Placement [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Class of Warrant or Right, Exercise Price of Warrants or Rights                         $ 7.00                                  
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures, Total                         $ 126,640                                  
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                         3,500                                  
Warrant Purchase Price Per Unit                         $ 45,000                                  
Proceeds from Issuance of Private Placement                         $ 600,000                                  
Warrants Issued                         44,324                                  
Chief Executive Officer [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross                                               1,900,000            
Share-based Compensation Arrangement by Share-based Payment Award, Plan Modification, Incremental Compensation Cost                                               $ 2,500,000 $ 400,000          
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting year                                               December 2022            
Former Board Of Director [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Share Based Compensation Restricted Stock Units $ 133,000                                                          
Dr. Rosenwald [Member] | Longterm Incentive Program [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period                 552,698         510,434                                
Mustang [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Stock Based compensation, authorized number of shares                                               8,610,774            
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized                                               8,610,774            
Stock Issued During Period, Value, New Issues                                               $ 56,000,000            
Warrants Issued number                                               2,152,693            
Proceeds from Fees Received                                               $ 5,600,000            
Percentage of Placement of Agent Fee                                               10.00%            
Warrants Issued on During Period                                               861,077            
Senior Vice President [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage 50.00%                                                          
Stock Issued During Period, Value, Issued for Services                                               $ 300,000 $ 1,200,000 $ 1,900,000        
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross                                     200,000                      
Share-based Compensation Arrangement by Share-based Payment Award, Plan Modification, Incremental Compensation Cost $ 3,700,000                                                          
Non-employee [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Share-based Compensation                                                   3,000,000        
Avenue Therapeutics, Inc. [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Shares Issued, Price Per Share             $ 6.00                                              
Mustang Bio, Inc [Member] | Private Placement [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Class of Warrant or Right, Exercise Price of Warrants or Rights                                         $ 8.50   $ 8.50              
Stock Issued During Period, Value, New Issues                                         $ 39,100,000                  
Mustang Bio, Inc [Member] | Market Offering [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Stock Issued During Period Shares warrants Exercised                                       2,500                    
Stock Issued During Period, Value of Warrants Excercised                                       $ 65,000                    
Checkpoint Therapeutics, Inc [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Equity Method Investment, Ownership Percentage                                               37.70%            
Stock Issued During Period, Value, New Issues                                               $ 57,800,000            
National Holdings Corporation [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Class of Warrant or Right, Exercise Price of Warrants or Rights                                         $ 3.25   $ 3.25              
Class of Warrant or Right, Number of Securities Called by Warrants or Rights             125,000                                              
National Holdings Corporation [Member] | Private Placement [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Stock Issued During Period Shares warrants Exercised                                       10                    
Payments of Stock Issuance Costs                                       $ 3,900,000                    
Private Placement Stock Units Shares To Be Issued                   10,000                   10,000         10,000          
Warrants Issued During Period                                               601,486            
National Securities Corp [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Payments for Other Fees       2,100,000                                                    
Payments for Fees       $ 2,100,000                                                    
Research and Development Expense [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Allocated Share-based Compensation Expense                                               $ 4,000,000 $ 4,700,000 5,800,000        
General and Administrative Expense [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Allocated Share-based Compensation Expense                                               10,000,000 7,400,000 8,500,000        
General and Administrative Expense [Member] | Longterm Incentive Program [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Share-based Compensation                                               $ 100,000 $ 18,000 2,200,000        
Restricted Stock [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Share Based Compensation Restricted Stock Units                                                   $ 400,000        
Deferred Compensation Arrangement with Individual, Shares Issued                                               230,000 230,000 290,000        
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Granted in Period, Fair Value                                               $ 3,600,000 $ 3,400,000          
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period                                               1,325,396 1,240,868          
Restricted Stock Units (RSUs) [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition                                               4 years 7 months 6 days            
Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options                                               $ 3,200,000            
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Granted in Period, Fair Value                                               $ 4,700,000 $ 1,800,000          
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period                                               1,128,750 641,000          
Restricted Stock Units (RSUs) [Member] | Senior Vice President [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross 1,000,000                                                          
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Number of Shares                                               150,000 150,000 300,000        
New Award [Member] | Senior Vice President [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Share-based Compensation Arrangement by Share-based Payment Award, Plan Modification, Incremental Compensation Cost $ 3,300,000                                                          
Old Award [Member] | Senior Vice President [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Share-based Compensation Arrangement by Share-based Payment Award, Plan Modification, Incremental Compensation Cost $ 400,000                                                          
Employee Stock Option [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Employee Stock Purchase Plan to eligible employees, Reckoning fair value percentage during offering period                   85.00%           85.00%       85.00%         85.00%       85.00%  
Employee Stock Purchase Plan to eligible employees, Number of shares purchased by employees 85                                                          
Common Stock issued in connection with the first ESPP offering   14,681               52,769 33,958         13,317               245,652            
Common Stock Par Or Stated Value Per Share $ 2.40                             $ 2.41                         $ 1.80  
Share Price                   $ 2.39 $ 2.82         $ 2.84       $ 2.39         $ 2.39       $ 2.12  
Proceeds from Stock Options Exercised                                               $ 27,000 $ 0 $ 200,000        
Common Stock, Capital Shares Reserved for Future Issuance                                               154,348            
Unvested Restricted Stock Units [Member]                                                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                                            
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition                                               1 year 6 months            
Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options                                               $ 3,400,000