Quarterly report pursuant to Section 13 or 15(d)

Fair Value Measurements - Changes in Fair Value of Financial Instruments (Detail)

v3.5.0.2
Fair Value Measurements - Changes in Fair Value of Financial Instruments (Detail) - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Dec. 31, 2015
Dec. 31, 2014
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]        
Balance $ 6,845 $ 4,095 $ 2,599 $ 4,160
Additions during the period 5,928      
Change in fair value of investments (1,800) (65)    
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings 13      
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Derivative Liability, Gain Loss Included in Earnings 105      
Balance 6,845 4,095 2,599 4,160
Warrant liabilities [Member]        
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]        
Balance 98   0  
Additions during the period 98      
Change in fair value of investments 0      
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings 0      
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Derivative Liability, Gain Loss Included in Earnings 0      
Balance 98   0  
Contingently Issuable Warrants [Member]        
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]        
Balance 853   114  
Additions during the period 634      
Change in fair value of investments 0      
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings 0      
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Derivative Liability, Gain Loss Included in Earnings 105      
Balance 853   114  
Helocyte Convertible Note, At Fair Value [Member]        
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]        
Balance 3,031   0  
Additions during the period 3,018      
Change in fair value of investments 0      
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings 13      
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Derivative Liability, Gain Loss Included in Earnings 0      
Balance 3,031   0  
Investment In Laser Device [Member]        
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]        
Balance 250 250 250 250
Additions during the period 0      
Change in fair value of investments 0 0    
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings 0      
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Derivative Liability, Gain Loss Included in Earnings 0      
Balance 250 250 250 250
Investment In Origo [Member]        
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]        
Balance 435 3,845 2,235 3,910
Additions during the period 0      
Change in fair value of investments (1,800) (65)    
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings 0      
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Derivative Liability, Gain Loss Included in Earnings 0      
Balance 435 $ 3,845 2,235 $ 3,910
Securities Owned, At Fair value [Member]        
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]        
Balance 2,178   0  
Additions during the period 2,178      
Change in fair value of investments 0      
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings 0      
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Derivative Liability, Gain Loss Included in Earnings 0      
Balance $ 2,178   $ 0