Condensed Consolidated Statement of Changes in Stockholders' Equity - USD ($) $ in Thousands |
Series A Preferred Stock [Member] |
Common Stock [Member] |
Common Shares Issuable [Member] |
Additional Paid-In Capital [Member] |
Accumulated Deficit [Member] |
Non-Controlling Interests [Member] |
Total |
Balance at Dec. 31, 2017 |
$ 1
|
$ 51
|
$ 500
|
$ 364,148
|
$ (312,127)
|
$ 67,929
|
$ 120,502
|
Balance (in shares) at Dec. 31, 2017 |
1,000,000
|
50,991,285
|
|
|
|
|
|
Stock-based compensation expense |
|
|
|
12,043
|
|
|
12,043
|
Issuance of restricted stock |
|
$ 2
|
|
(2)
|
|
|
|
Issuance of restricted stock (in shares) |
|
1,809,421
|
|
|
|
|
|
Issuance of common stock for at-the-market offering, net |
|
$ 3
|
|
6,956
|
|
|
6,959
|
Issuance of common stock for at-the-market offering, net (in shares) |
|
2,668,756
|
|
|
|
|
|
Issuance of common stock under ESPP |
|
|
|
128
|
|
|
128
|
Issuance of common stock under ESPP (in shares) |
|
43,707
|
|
|
|
|
|
Issuance of subsidiaries' common shares for license expenses |
|
|
|
229
|
|
|
229
|
Disposal of National |
|
|
|
14,376
|
|
|
14,376
|
Subsidiary's offering cost |
|
|
|
22,668
|
|
|
22,668
|
Subsidiary's ATM offering, net |
|
|
|
7,726
|
|
|
7,726
|
Exercise of partner company's warrants for cash |
|
|
|
181
|
|
|
181
|
Adjustments To Additional Paid In Capital At Market Offering Costs |
|
|
|
(240)
|
|
|
(240)
|
Contribution of capital for 2017 bonuses |
|
|
|
1,000
|
|
|
1,000
|
Common shares issuable for 2017 Subordinated Note Financing interest expense |
|
|
495
|
|
|
|
495
|
Common shares issued for 2017 Subordinated Note Financing interest expense |
|
|
(500)
|
1,478
|
|
|
978
|
Common shares issued for 2017 Subordinated Note Financing interest expense (in shares) |
|
436,281
|
|
|
|
|
|
Common shares issued for Opus interest expense |
|
|
|
574
|
|
|
574
|
Common shares issued for Opus interest expense (in shares) |
|
234,030
|
|
|
|
|
|
Preferred A dividends declared and paid |
|
|
|
(1,758)
|
|
|
(1,758)
|
2017 Preferred A offering cost adjustment |
|
|
|
1,297
|
|
|
1,297
|
Non-controlling interest in subsidiaries |
|
|
|
(22,189)
|
|
22,189
|
|
Net loss attributable to non-controlling interest |
|
|
|
|
|
(43,254)
|
(43,254)
|
Net loss attributable to common stockholders |
|
|
|
|
(59,267)
|
|
(59,267)
|
Balance at Sep. 30, 2018 |
$ 1
|
$ 56
|
495
|
408,615
|
(371,394)
|
46,864
|
84,637
|
Balance (in shares) at Sep. 30, 2018 |
1,000,000
|
56,183,480
|
|
|
|
|
|
Balance at Jun. 30, 2018 |
$ 1
|
$ 54
|
776
|
397,858
|
(354,756)
|
52,332
|
96,265
|
Balance (in shares) at Jun. 30, 2018 |
1,000,000
|
53,987,074
|
|
|
|
|
|
Stock-based compensation expense |
|
|
|
4,096
|
|
|
4,096
|
Issuance of restricted stock (in shares) |
|
251,147
|
|
|
|
|
|
Issuance of common stock for at-the-market offering, net |
|
$ 2
|
|
2,887
|
|
|
2,889
|
Issuance of common stock for at-the-market offering, net (in shares) |
|
1,537,921
|
|
|
|
|
|
Issuance of subsidiaries' common shares for license expenses |
|
|
|
206
|
|
|
206
|
Disposal of National |
|
|
|
934
|
|
|
934
|
Subsidiary's offering cost |
|
|
|
11
|
|
|
11
|
Subsidiary's ATM offering, net |
|
|
|
7,726
|
|
|
7,726
|
Adjustments To Additional Paid In Capital At Market Offering Costs |
|
|
|
(99)
|
|
|
(99)
|
Contribution of capital for 2017 bonuses |
|
|
|
1,000
|
|
|
1,000
|
Common shares issuable for 2017 Subordinated Note Financing interest expense |
|
|
495
|
|
|
|
495
|
Common shares issued for 2017 Subordinated Note Financing interest expense |
|
|
(489)
|
489
|
|
|
|
Common shares issued for 2017 Subordinated Note Financing interest expense (in shares) |
|
173,308
|
|
|
|
|
|
Common shares issued for Opus interest expense |
|
|
(287)
|
574
|
|
|
287
|
Common shares issued for Opus interest expense (in shares) |
|
234,030
|
|
|
|
|
|
Preferred A dividends declared and paid |
|
|
|
(586)
|
|
|
(586)
|
Non-controlling interest in subsidiaries |
|
|
|
(6,481)
|
|
6,481
|
|
Net loss attributable to non-controlling interest |
|
|
|
|
|
(11,949)
|
(11,949)
|
Net loss attributable to common stockholders |
|
|
|
|
(16,638)
|
|
(16,638)
|
Balance at Sep. 30, 2018 |
$ 1
|
$ 56
|
495
|
408,615
|
(371,394)
|
46,864
|
84,637
|
Balance (in shares) at Sep. 30, 2018 |
1,000,000
|
56,183,480
|
|
|
|
|
|
Balance at Dec. 31, 2018 |
$ 1
|
$ 58
|
659
|
397,408
|
(396,274)
|
17,891
|
19,743
|
Balance (in shares) at Dec. 31, 2018 |
1,000,000
|
57,845,447
|
|
|
|
|
|
Stock-based compensation expense |
|
|
|
10,423
|
|
|
10,423
|
Issuance of restricted stock |
|
$ 2
|
|
(2)
|
|
|
|
Issuance of restricted stock (in shares) |
|
1,842,034
|
|
|
|
|
|
Issuance of preferred A for at-the-market offering, net |
|
|
|
523
|
|
|
523
|
Issuance of preferred A for at-the-market offering, net (in shares) |
26,111
|
|
|
|
|
|
|
Issuance of common stock for at-the-market offering, net |
|
$ 9
|
|
15,789
|
|
|
15,798
|
Issuance of common stock for at-the-market offering, net (in shares) |
|
8,604,469
|
|
|
|
|
|
Issuance of common stock under ESPP |
|
|
|
60
|
|
|
60
|
Issuance of common stock under ESPP (in shares) |
|
54,221
|
|
|
|
|
|
Issuance of subsidiaries' common shares for license expenses |
|
|
(164)
|
164
|
|
|
|
Subsidiary's offering cost |
|
|
|
61,036
|
|
|
61,036
|
Subsidiary's ATM offering, net |
|
|
|
29,680
|
|
|
29,680
|
Issuance of partner company warrants in conjunction with Horizon Notes |
|
|
|
888
|
|
|
888
|
Common shares issuable for 2017 Subordinated Note Financing interest expense |
|
|
500
|
|
|
|
500
|
Common shares issued for 2017 Subordinated Note Financing interest expense |
|
$ 1
|
(495)
|
1,468
|
|
|
974
|
Common shares issued for 2017 Subordinated Note Financing interest expense (in shares) |
|
1,330,450
|
|
|
|
|
|
Common shares issuable for Opus interest expense |
|
|
281
|
|
|
|
281
|
Common shares issued for Opus interest expense |
|
|
(281)
|
506
|
|
|
225
|
Common shares issued for Opus interest expense (in shares) |
|
262,088
|
|
|
|
|
|
Common shares issued for Opus debt |
|
|
|
500
|
|
|
500
|
Common shares issued for Opus debt (in shares) |
|
396,825
|
|
|
|
|
|
Preferred A dividends declared and paid |
|
|
|
(1,773)
|
|
|
(1,773)
|
Non-controlling interest in subsidiaries |
|
|
|
(70,702)
|
|
70,702
|
|
Write off of Partner company note receivable |
|
|
|
(2)
|
|
|
(2)
|
Deconsolidation of Caelum non-controlling interest |
|
|
|
|
|
4,849
|
4,849
|
Net loss attributable to non-controlling interest |
|
|
|
|
|
(44,237)
|
(44,237)
|
Net loss attributable to common stockholders |
|
|
|
|
(24,468)
|
|
(24,468)
|
Balance at Sep. 30, 2019 |
$ 1
|
$ 70
|
500
|
445,966
|
(420,742)
|
49,205
|
75,000
|
Balance (in shares) at Sep. 30, 2019 |
1,026,111
|
70,335,534
|
|
|
|
|
|
Balance at Jun. 30, 2019 |
$ 1
|
$ 68
|
490
|
439,295
|
(407,980)
|
57,946
|
89,820
|
Balance (in shares) at Jun. 30, 2019 |
1,000,000
|
68,138,203
|
|
|
|
|
|
Stock-based compensation expense |
|
|
|
3,741
|
|
|
3,741
|
Issuance of restricted stock (in shares) |
|
177,292
|
|
|
|
|
|
Issuance of preferred A for at-the-market offering, net |
|
|
|
523
|
|
|
523
|
Issuance of preferred A for at-the-market offering, net (in shares) |
26,111
|
|
|
|
|
|
|
Issuance of common stock for at-the-market offering, net |
|
$ 1
|
|
1,930
|
|
|
1,931
|
Issuance of common stock for at-the-market offering, net (in shares) |
|
1,213,643
|
|
|
|
|
|
Subsidiary's offering cost |
|
|
|
52
|
|
|
52
|
Subsidiary's ATM offering, net |
|
|
|
3,341
|
|
|
3,341
|
Common shares issuable for 2017 Subordinated Note Financing interest expense |
|
|
500
|
|
|
|
500
|
Common shares issued for 2017 Subordinated Note Financing interest expense |
|
$ 1
|
(490)
|
489
|
|
|
|
Common shares issued for 2017 Subordinated Note Financing interest expense (in shares) |
|
317,804
|
|
|
|
|
|
Common shares issued for Opus interest expense |
|
|
|
165
|
|
|
165
|
Common shares issued for Opus interest expense (in shares) |
|
91,767
|
|
|
|
|
|
Common shares issued for Opus debt |
|
|
|
500
|
|
|
500
|
Common shares issued for Opus debt (in shares) |
|
396,825
|
|
|
|
|
|
Preferred A dividends declared and paid |
|
|
|
(601)
|
|
|
(601)
|
Non-controlling interest in subsidiaries |
|
|
|
(3,467)
|
|
3,467
|
|
Write off of Partner company note receivable |
|
|
|
(2)
|
|
|
(2)
|
Net loss attributable to non-controlling interest |
|
|
|
|
|
(12,208)
|
(12,208)
|
Net loss attributable to common stockholders |
|
|
|
|
(12,762)
|
|
(12,762)
|
Balance at Sep. 30, 2019 |
$ 1
|
$ 70
|
$ 500
|
$ 445,966
|
$ (420,742)
|
$ 49,205
|
$ 75,000
|
Balance (in shares) at Sep. 30, 2019 |
1,026,111
|
70,335,534
|
|
|
|
|
|