Annual report pursuant to Section 13 and 15(d)

Income Taxes

v2.4.1.9
Income Taxes
 12 Months Ended
Dec. 31, 2014
Income Tax Disclosure [Abstract]  
Income Tax Disclosure
17. Income Taxes 
 
The Company has incurred net operating losses since inception. The Company has not reflected any benefit of such net operating loss carryforwards (“NOL”) in the accompanying consolidated financial statements and has established a full valuation allowance of $50.6 million against its deferred tax assets.   
 
Deferred income taxes reflect the net tax effects of (a) temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes, and (b) operating losses and tax credit carryforwards.
  
The significant components of the Company’s deferred tax assets consisted of the following:
 
 
As of December 31,
 
 
 
2014
 
2013
 
($ in thousands)
 
 
 
 
 
 
 
Deferred tax assets:
 
 
 
 
 
 
 
Net operating loss carryforwards
 
$
38,974
 
$
31,450
 
Amortization of up-front fees
 
 
2,668
 
 
2,865
 
Amortization of in-process R&D
 
 
525
 
 
460
 
Stock compensation
 
 
4,512
 
 
2,827
 
Accruals and reserves
 
 
518
 
 
854
 
Tax credits
 
 
3,856
 
 
2,686
 
Total deferred tax assets
 
 
51,053
 
 
41,142
 
Valuation allowance
 
 
(50,567)
 
 
(41,142)
 
Net deferred tax assets
 
$
486
 
$
—
 
Deferred tax liabilities:
 
 
 
 
 
 
 
Unrealized gain/loss on investment
 
$
(486)
 
$
—
 
Total deferred tax assets, net
 
$
—
 
$
—
 
 
 A reconciliation of the statutory tax rates and the effective tax rates is as follows:
 
 
 
For the Year Ended December 31,
 
 
 
2014
 
 
2013
 
 
2012
 
Percentage of pre-tax income:
 
 
 
 
 
 
 
 
 
 
 
 
U.S. federal statutory income tax rate
 
 
35
%
 
 
35
%
 
 
35
%
State taxes, net of federal benefit
 
 
5
%
 
 
4
%
 
 
4
%
Credits
 
 
6
%
 
 
4
%
 
 
1
%
Non-deductible items
 
 
(1)
%
 
 
(2)
%
 
 
(2)
%
Other (1)
 
 
—
%
 
 
(1)
%
 
 
(5)
%
Change in valuation allowance
 
 
(45)
%
 
 
(40)
%
 
 
(33)
%
Effective income tax rate
 
 
—
%
 
 
—
%
 
 
—
%
 
(1) – Other consists of: in 2014 (0%), in 2013 state NOL true-up (1%), and in 2012 state rate change (5%).
 
Realization of the future tax benefits is dependent on the Company’s ability to generate sufficient taxable income within the carryforward period. The Company has concluded, based on the weight of available evidence, that its net deferred tax assets are not more likely than not to be realized in the future. Management has considered the Company’s history of cumulative net losses incurred since inception and concluded that it is more likely than not that the Company will not realize the benefits of the deferred tax assets. Accordingly, a full valuation allowance has been established against the deferred tax assets as of December 31, 2014 and 2013. The valuation allowance increased by $9.4 million from December 31, 2013 to December 31, 2014, primarily due to an increase in net operating losses.
 
As of December 31, 2014, the Company has federal net operating loss carryforwards and research and development tax credit carryforwards of approximately $104.0 million and $3.8 million respectively,, including an orphan drug tax credit of $2.1 million, which expire beginning in 2026 and 2029, respectively. As of December 31, 2014, the Company has state net operating loss carryforwards of approximately $50.7 million, which expires beginning in 2031. Utilization of the net operating loss carryforwards and credits may be subject to a substantial annual limitation due to the ownership change limitations provided by the Internal Revenue Code of 1986, as amended, or the IRC, and similar state provisions. The Company has not performed a detailed analysis to determine whether an ownership change under Section 382 of the IRC has occurred. The effect of an ownership change would be the imposition of an annual limitation on the use of net operating loss carryforwards attributable to periods before the change. Any limitation may result in expiration of a portion of the NOL or research and development credit carryforwards before utilization. Approximately $1.8 million of the federal net operating loss carryforward and $1.6 million of the state net operating loss carryforward will result in an increase to additional paid-in capital if and when these carryforwards are used to reduce income taxes payable.
 
As of December 31, 2014, the Company had no unrecognized tax benefits and does not anticipate any significant change to the unrecognized tax benefit balance. The Company would classify interest and penalties related to uncertain tax positions in income tax expense, if applicable. There was no interest expense or penalties related to unrecognized tax benefits recorded through December 31, 2014. The tax years 2006 through 2014 remain open to examination by one or more major taxing jurisdictions to which the Company is subject.