Annual report pursuant to Section 13 and 15(d)

Warrants to Purchase Common Stock (Details Textual)

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Warrants to Purchase Common Stock (Details Textual) (USD $)
1 Months Ended 12 Months Ended 12 Months Ended 12 Months Ended 12 Months Ended 1 Months Ended 1 Months Ended 12 Months Ended
Aug. 31, 2012
Apr. 30, 2012
Dec. 31, 2012
Oct. 05, 2012
Aug. 16, 2012
Dec. 31, 2011
Dec. 31, 2012
National Securities Corporation [Member]
Sep. 30, 2011
National Securities Corporation [Member]
Dec. 31, 2012
Debt Placement Agent Warrants [Member]
Apr. 26, 2010
Debt Placement Agent Warrants [Member]
Apr. 26, 2010
Debt Placement Agent Warrants [Member]
Series A [Member]
Apr. 26, 2010
Debt Placement Agent Warrants [Member]
2008 Senior Convertible Notes [Member]
Series A [Member]
Apr. 26, 2010
Debt Placement Agent Warrants [Member]
2009 Senior Convertible Notes [Member]
Series A [Member]
Dec. 31, 2012
PCP Warrants [Member]
Dec. 31, 2009
PCP Warrants [Member]
Dec. 31, 2011
PCP Warrants [Member]
Series A [Member]
Apr. 26, 2010
PCP Warrants [Member]
Series A [Member]
Dec. 31, 2012
Preferred Stock Placement Warrants [Member]
Dec. 31, 2012
Preferred Stock Placement Warrants [Member]
Series A [Member]
Dec. 31, 2012
Preferred Stock Placement Warrants [Member]
Maximum [Member]
Series A [Member]
Dec. 31, 2012
Preferred Stock Placement Warrants [Member]
Minimum [Member]
Series A [Member]
Dec. 31, 2012
Non-employee warrants [Member]
Aug. 31, 2012
Non-employee warrants [Member]
Apr. 30, 2012
Non-employee warrants [Member]
Dec. 31, 2011
Non-employee warrants [Member]
Sep. 30, 2011
Non-employee warrants [Member]
Mar. 31, 2011
Non-employee warrants [Member]
Feb. 28, 2011
Non-employee warrants [Member]
Nov. 30, 2010
Non-employee warrants [Member]
Dec. 18, 2012
Non-employee warrants [Member]
Aug. 28, 2012
Non-employee warrants [Member]
Aug. 16, 2012
Non-employee warrants [Member]
Apr. 02, 2012
Non-employee warrants [Member]
Nov. 22, 2010
Non-employee warrants [Member]
Sep. 30, 2011
Non-employee warrants [Member]
Maximum [Member]
Sep. 30, 2011
Non-employee warrants [Member]
Minimum [Member]
Apr. 02, 2012
Warrants to Purchase Series C Shares [Member]
Dec. 31, 2012
Warrants to Purchase Series C Shares [Member]
Common Stock [Member]
Apr. 02, 2012
Warrants to Purchase Series C Shares [Member]
Common Stock [Member]
Nov. 15, 2011
Warrants to Purchase Series C Shares [Member]
Common Stock [Member]
Warrants to Purchase Common Stock (Textual) [Abstract]                                                                                
Period of Issued Warrants                 7 years         5 years       7 years                 10 years 5 years 5 years                      
Notes Principal Amount Percentage                 10.00%   10.00%       40.00%   40.00%                                              
Warrant exercise price         5.72   5.59   1.00     9.23 9.23   1.00 6.15 9.23   8.39           6.00 2.95 1.37 1.37   4.88 5.65 5.72 1.37 9.23            
Issued warrants to purchase common stock         20,000   461,263         48,510 41,716     40,787 27,175   258,421           5,000 75,000 60,000 50,000   35,000 73,009 25,000 25,000 41,716            
Fair value of the warrant         $ 92,000         $ 200,000   $ 100,000 $ 100,000       $ 47,000 $ 600,000             $ 19,100 $ 144,000 $ 98,000 $ 69,000   $ 103,000   $ 113,000   $ 38,000            
Exercise price percentage                     110.00%           110.00%                                              
Volatility 104.51%                                     94.40% 92.00% 97.45% 110.30%   91.10%   95.40% 93.20% 93.70%           96.30% 90.80%   92.40%    
Risk free rate 1.06%                                     3.30% 2.00% 0.28% 0.83%   0.40%   3.58% 2.65% 1.40%           0.90% 0.40%   0.93%    
Contractual term 6 years                                   7 years     3 years 5 years   3 years   10 years 5 years 5 years           5 years 3 years   5 years    
Dividend yield 0.00%                                         0.00% 0.00%   0.00% 0.00% 0.00% 0.00%                        
Estimated per share fair value                                     $ 3.45                             $ 1.96       $ 8.00    
Warrants Expiration Terms The warrant expires on the sixth anniversary of its issuance date                                         The warrant expires on the third anniversary of its issuance date The warrant expires on the fifth anniversary of its issuance date   The warrants expire on the third anniversary of its issuance date The warrants expire on the third or fifth anniversaries of their issuance dates.                            
Warrants issued                                                                 20,970              
Warrant fair value                                               $ 8.50                                
Warrant vest                                                 2 years 2 years 6 months                          
Fee paid to National Securities Corporation as consideration for its services as the placement agent             10.00%                                                                  
Common Stock, shares issued     24,400,754 3,361   18,604,245                                                                 534  
Gross proceeds of the issuance in connection with the Company's Series C Share offering             2,600,000                                                                  
Duration of issued warrant             5 years                                                                  
Fair value of warrants reduction in carrying amount in share               1,300,000                                                                
Amount charge due to mark-to-market valuation of warrants exercisable for common stock                                                                               1,400,000
Final fair value of common stock                                                                           $ 2,700,000    
Common stock shares exercised                                                                         2,986      
Fair market value of common stock on the date of exercise   $ 6.81                                                                            
Exercise price of the warrants   $ 5.59