Annual report pursuant to Section 13 and 15(d)

Debt and Interest- Additional Information (Detail)

v3.3.1.900
Debt and Interest- Additional Information (Detail) - USD ($)
 1 Months Ended 12 Months Ended
Oct. 13, 2015
Oct. 30, 2015
Mar. 31, 2015
Feb. 13, 2014
Aug. 31, 2012
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Oct. 31, 2015
Sep. 18, 2015
Debt [Line Items]                    
Term loan           $ 24,009,000 $ 14,009,000      
Warrant to purchase common stock           7.00        
Warrant exercise price           $ 2,500       $ 7.00
Fair value of the warrant volatility           9.30%        
Fair value of risk-free interest rate           0.10%        
Debt Discount           $ 314,000 0 $ 0    
Debt discount recorded           835,000 6,000      
Interest Expense, Debt           1,500,000 1,300,000 1,900,000    
Amortization of Financing Costs $ 300,000         $ 700,000 4,000,000      
Percentage of Cash Flow Pursuant to ASC 470           10.00%        
Fair Value Adjustment of Warrants           $ 438,000 0 0    
Warrant [Member]                    
Debt [Line Items]                    
Approximate fair value of the warrant         $ 323,000          
Israel Discount Bank Of New York [Member]                    
Debt [Line Items]                    
Debt Instrument, Face Amount       $ 15,000,000            
Notes Payable       14,000,000   $ 14,000,000        
IDB Promissory Note Payable [Member]                    
Debt [Line Items]                    
Debt Instrument, Interest Rate, Stated Percentage           2.25%        
Debt Instrument, Face Amount       15,000,000            
Amortization of Financing Costs           $ 5,000,000        
IDB Promissory Note Payable [Member] | Minimum [Member]                    
Debt [Line Items]                    
Debt Instrument, Unused Borrowing Capacity, Amount       100,000            
Loan Agreement [Member]                    
Debt [Line Items]                    
Interest rate         interest at a rate per annum equal to the greater of (i) 9.25% or (ii) 9.25% plus the sum of the prevailing prime rate minus 3.25%          
Maturity Date         Mar. 01, 2016          
Interest payment term         interest-only payments for the initial 12 months and thereafter requires repayment of the principal balance with interest in 30 monthly installments          
Debt Discount         $ 939,000          
NSC Notes Payable [Member]                    
Debt [Line Items]                    
Term loan           $ 10,000,000 0      
Debt Instrument, Interest Rate, Stated Percentage           8.00%        
Debt Instrument, Fee Amount           $ 900,000        
Interest Expense, Debt           690,000 0 0    
Accretion of Discount           $ 309,000 0 0    
Notes Payable     $ 10,000,000              
Debt Instrument, Maturity Date, Description     36 Months     Mar - 2018        
Debt Instrument, Interest Rate, Effective Percentage           14.00%        
Amortization of Financing Costs           $ 300,000        
Hercules Note Payble [Member]                    
Debt [Line Items]                    
Debt Instrument, Periodic Payment, Interest       100,000            
Debt Instrument, Periodic Payment       14,000,000   14,000,000        
Interest Expense, Debt [1]           0 845,000 1,767,000    
Accretion of Discount           0 400,000 400,000    
Amortization of Financing Costs           $ 0 43,000 20,000    
Hercules Note Payble [Member] | IDB Promissory Note Payable [Member]                    
Debt [Line Items]                    
Amortization of Financing Costs             300,000      
Hercules Note Payble [Member] | Loan Agreement [Member]                    
Debt [Line Items]                    
Debt Instrument, Periodic Payment, Principal       13,200,000            
Debt Instrument Term Charges       400,000            
Debt Instrument, Fee Amount       $ 300,000            
Hercules Debt Agreement [Member]                    
Debt [Line Items]                    
Interest Expense, Debt             800,000 1,700,000    
Accretion of Discount             $ 400,000 $ 300,000    
Hercules Debt Agreement [Member] | Warrant [Member]                    
Debt [Line Items]                    
Fair value of the warrant volatility         87.20%          
Fair value of risk-free interest rate         1.10%          
Hercules Debt Agreement [Member] | Loan Agreement [Member]                    
Debt [Line Items]                    
Term loan         $ 15,000,000          
Received net proceeds         14,700,000          
Subsequent private placement         $ 2,000,000          
Warrant to purchase common stock         73,009          
Warrant exercise price         $ 5.65          
Charges on termination of the loan stated percentage         2.65%          
Charges on termination of the loan, amount         $ 398,000          
Fees related to the loan agreement         $ 218,000          
Interest rate for amortize loan discounts         12.30%          
NSC [Member]                    
Debt [Line Items]                    
Debt Instrument, Term           10 years        
Checkpoint [Member] | NSC Notes Payable [Member]                    
Debt [Line Items]                    
Fees related to the loan agreement           $ 2,800,000        
Avenue [Member] | NSC Notes Payable [Member]                    
Debt [Line Items]                    
Fees related to the loan agreement           $ 3,000,000        
warrant to NSC [Member]                    
Debt [Line Items]                    
Approximate fair value of the warrant   $ 600,000                
Debt discount recorded                 $ 200,000  
Share-based Compensation Arrangement by Share-based Payment Award, Non-Option Equity Instruments, Granted   139,592                
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Exercisable Options, Weighted Average Exercise Price   $ 0.0001                
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period   10 years                
Share-based Goods and Nonemployee Services Transaction, Valuation Method, Expected Term   10 years                
Fair Value Adjustment of Warrants   $ 400,000                
Contingently Issuable Warrants issued in connection with NSC Note Avenue [Member]                    
Debt [Line Items]                    
Debt Instrument, Unamortized Discount (Premium), Net, Total                 $ 114,000  
[1] Interest expense related to the Company’s loan with Hercules was $0.8 million and 1.7 million, including $0.4 million and $0.3 million related to accretion of the debt discount for the years ended December 31, 2014 and 2013 respectively.