Annual report pursuant to Section 13 and 15(d)

Asset Purchase Agreements (Narrative) (Details)

v3.24.1
Asset Purchase Agreements (Narrative) (Details)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended 24 Months Ended
Jul. 28, 2023
USD ($)
Apr. 21, 2023
USD ($)
Oct. 11, 2022
USD ($)
Feb. 24, 2021
USD ($)
Dec. 31, 2023
USD ($)
D
Nov. 30, 2023
USD ($)
Oct. 31, 2023
USD ($)
Sep. 30, 2023
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2023
USD ($)
Jul. 31, 2022
USD ($)
Proceeds from Issuance of Common Stock                 $ 2,041 $ 6,053    
Payments of milestones                     $ 500  
Collaboration revenue                 5,229 1,882    
Sale of Stock, Consideration Received on Transaction           $ 8,900 $ 10,000          
Asset purchase agreement to acquire Aevitas proprietary rights                        
Fair value of Aevitas interest retained   $ 2,600                    
Cyprium | Sentnyl                        
Contingent liability         $ 4,500       4,500   4,500  
Upfront fees payment       $ 8,000 8,000              
Collaboration revenue                 700 $ 1,900    
Avenue                        
Proceeds from Issuance of Common Stock     $ 10,300     $ 5,000            
Avenue | InvaGen                        
Percentage of contingent fee payable                       7.50%
Contingent fee payable from proceeds of future financing                       $ 4,000
Aevitas                        
Loss from deconsolidation of Aevitas                 3,400      
Aevitas | Maximum | Asset purchase agreement to acquire Aevitas proprietary rights                        
Upfront payment to be paid   $ 140,000                    
Mustang                        
Expenses under manufacturing services agreement               $ 4,100        
Asset acquisition, minimum commitment amount $ 8,000                      
Manufacturing services in excess of the minimum commitment $ 3,000                      
Asset acquisition, minimum commitment amount payment, term 2 years                      
Asset acquisition, minimum commitment amount paid, percentage 25.00%                      
Mustang | Manufacturing Services Agreement [Member]                        
Reimbursed costs               2,400        
Receivable         $ 3,200       3,200   3,200  
Mustang | UBriGene                        
Consideration Transferred $ 6,000                      
Contingent liability $ 5,000                      
Contingent consideration period 2 years                      
Contingent liability, Issuance of equity securities $ 10,000                      
Contingent consideration, Proposed lease period 2 years                      
Loss on sale of asset               $ 1,500        
Transaction Related Expenses $ 300                      
SPMA | Cyprium | Sentnyl | Manufacturing Services Agreement [Member]                        
Number of days to assume control over development of CUTX-101 in the event that CUTX-101 NDA approval has not been obtained | D         45              
FDA approval of the NDA | Cyprium | Sentnyl | Maximum                        
Payments of milestones       $ 129,000                
Annual net sales up to $75 million | Cyprium | Sentynl APA                        
Contingent liability         $ 75,000       75,000   75,000  
Royalty on net sales to be received (in percent)         3.00%              
Annual net sales between $75 million and $100 million | Cyprium | Sentynl APA                        
Consideration Transferred         $ 100,000              
Contingent liability         $ 75,000       $ 75,000   $ 75,000  
Royalty on net sales to be received (in percent)         8.75%              
Annual net sales in excess of $100 million | Cyprium | Sentynl APA                        
Consideration Transferred         $ 100,000              
Royalty on net sales to be received (in percent)         12.50%