Annual report pursuant to Section 13 and 15(d)

Income Taxes (Deferred Tax Assets and Liabilities) (Details)

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Income Taxes (Deferred Tax Assets and Liabilities) (Details) - USD ($)
$ in Thousands
Dec. 31, 2020
Dec. 31, 2019
Deferred tax assets:    
Net operating loss carryforwards $ 152,295 $ 125,657
Amortization of license fees 20,628 17,077
Amortization of in-process R&D 415 449
Stock compensation 14,732 13,280
Lease liability 7,306 7,454
Accruals and reserves 1,570 1,810
Tax credits 16,326 12,716
Startup costs 54 58
Unrealized gain/loss on investments 1,075 716
State taxes 41 0
Reserve on Sales Return, Discount and Bad Debt 1,455 0
Total deferred tax assets 215,897 179,217
Less: valuation allowance (203,930) (168,223)
Net deferred tax assets 11,967 10,994
Deferred tax liabilities:    
Right of use asset (6,050) (6,280)
Fair Value adjustment on investment in Caelum (4,804) (2,879)
Basis in subsidiary (1,113) (1,835)
Total deferred tax assets, net $ 0 $ 0