Quarterly report pursuant to Section 13 or 15(d)

Subsequent Events (Details)

v3.19.2
Subsequent Events (Details) - USD ($)
Aug. 07, 2019
Jul. 18, 2019
Jul. 01, 2019
Jun. 30, 2019
Dec. 31, 2018
Subsequent Event [Line Items]          
Common Stock, Shares, Issued       68,138,203 68,138,203
Common Stock, Par or Stated Value Per Share       $ 0.001 $ 0.001
Long-term Debt       $ 90,242,000 $ 84,406,000
Opus Credit Facility [Member]          
Subsequent Event [Line Items]          
Long-term Debt       $ 9,500,000 $ 9,500,000
Subsequent Events [Member]          
Subsequent Event [Line Items]          
Common Stock, Shares, Issued   396,825      
Common Stock, Par or Stated Value Per Share   $ 1.26      
Long-term Debt   $ 500,000      
Subsequent Events [Member] | 2017 Subordinated Note [Member]          
Subsequent Event [Line Items]          
Long-term Debt $ 28,400,000        
Subsequent Events [Member] | 2018 Venture Notes [Member]          
Subsequent Event [Line Items]          
Long-term Debt 21,700,000        
Subsequent Events [Member] | Opus Credit Facility [Member]          
Subsequent Event [Line Items]          
Long-term Debt 5,200,000   $ 500,000    
Subsequent Events [Member] | NAM Biotech Fund II, LLC [Member] | 2017 Subordinated Note [Member]          
Subsequent Event [Line Items]          
Long-term Debt 12,300,000        
Subsequent Events [Member] | NAM Special Situations Fund I QP [Member] | 2017 Subordinated Note [Member]          
Subsequent Event [Line Items]          
Long-term Debt 16,100,000        
Subsequent Events [Member] | NSC Biotech Opportunities Fund, LLC [Member] | 2018 Venture Notes [Member]          
Subsequent Event [Line Items]          
Long-term Debt 5,100,000        
Subsequent Events [Member] | NSC Biotech Opportunities QP Fund, LLC [Member] | 2018 Venture Notes [Member]          
Subsequent Event [Line Items]          
Long-term Debt $ 16,600,000