The following table shows the details of interest expense for all debt arrangements during the periods presented. Interest expense includes contractual interest and amortization of the debt discount and amortization of fees represents fees associated with loan transaction costs, amortized over the life of the loan: 

 

		Three Months Ended March 31,
($in thousands)		2018			2017
IDB Note
Interest		$	84		$	82
Total IDB Note			84			82
NSC Debt
Interest			-			71
Amortization of fees			-			38
Total NSC Debt			-			109
2017 Subordinated Note Financing
Interest			1,048			-
Amortization of fees			21			-
Total 2017 Subordinated Note Financing			1,069			-
Opus Credit Facility
Interest			281			232
Amortization of fees			319			208
Total Opus Note			600			440
2018 Venture Notes
Interest			56			-
Amortization of fees			1			-
Total 2018 Venture Notes			57			-
LOC Fees
Interest			7			8
Total LOC			7			8
Helocyte Convertible Note
Interest			68			54
Financing fee			-			1
Total Helocyte Convertible Note			68			55
Avenue Convertible Note
Financing fee			-			3
Total Avenue Convertible Note			-			3
Caelum Convertible Note
Interest			196			-
Total Caelum Convertible Note			196			-
Other
Interest			2			1
Total Other			2			1
Total Interest Expense and Financing Fee		$	2,083		$	698