Quarterly report pursuant to Section 13 or 15(d)

Stockholders' Equity (Narrative) (Details)

v3.24.3
Stockholders' Equity (Narrative) (Details)
1 Months Ended 3 Months Ended 9 Months Ended
Jul. 25, 2024
$ / shares
shares
Jan. 01, 2024
shares
Jan. 01, 2023
USD ($)
shares
May 31, 2024
shares
Jan. 31, 2024
USD ($)
$ / shares
shares
Aug. 31, 2020
$ / shares
shares
Sep. 30, 2024
USD ($)
Y
$ / shares
shares
Sep. 30, 2023
USD ($)
Sep. 30, 2024
USD ($)
Y
$ / shares
shares
Sep. 30, 2023
USD ($)
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Stock-based compensation expense             $ 6,573,000 $ 4,377,000 $ 16,429,000 $ 13,325,000
Interest expense             $ 2,236,000 1,877,000    
Direct offering                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Exercise price of warrants | $ / shares         $ 3.21          
Shares Issued, Price Per Share | $ / shares             $ 1.65   $ 1.65  
Warrant expiration term         5 years          
2024 Oaktree Note                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Warrants issued | shares 506,390                  
Exercise price of warrants | $ / shares $ 2.0735                  
Percentage of market price of common stock for additional warrants 95.00%                  
Shares Issued, Price Per Share | $ / shares $ 2.0735                  
Interest expense             $ 861,000      
2024 Oaktree Note | 2024 Oaktree Warrants                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Yield value             1,300,000   $ 1,300,000  
Warrants, fair value             $ 1,300,000   $ 1,300,000  
2024 Oaktree Note | Volatility                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Warrant liability, measurement input             0.9052   0.9052  
2024 Oaktree Note | Risk-free interest rate                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Warrant liability, measurement input             0.0418   0.0418  
2024 Oaktree Note | Expected term in years                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Warrant liability, measurement input | Y             7   7  
2024 Oaktree Note | Direct offering                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Exercise price of warrants | $ / shares             $ 1.65   $ 1.65  
Interest expense                 $ 20,000  
2020 Oaktree Note                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Percentage of market price of common stock for additional warrants           95.00%        
Shares Issued, Price Per Share | $ / shares           $ 8.14        
Interest expense             $ 440,000 1,425,000    
2020 Oaktree Note | Registered Offering | 2024 Oaktree Warrants                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Exercise price of warrants | $ / shares             $ 7.2392   $ 7.2392  
Interest expense                 $ 27,000  
Number of warrants issued | shares             14,450   14,450  
2013 Plan                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Share based compensation, additional shares authorized | shares       10,000,000.0            
Stock based compensation, shares available for issuance | shares             10,000,000.0   10,000,000.0  
2012 Employee Stock Purchase Plan                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Share based compensation, additional shares authorized | shares       1,000,000.0            
Stock based compensation, shares available for issuance | shares             1,000,000.0   1,000,000.0  
Long-Term Incentive Program                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Stock-based compensation expense             $ 1,700,000 1,500,000 $ 5,000,000.0 4,400,000
Fair value of stock granted     $ 800,000   $ 700,000          
LTIP, Percentage of outstanding shares   1.00% 1.00%              
Maximum | Direct offering                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Warrants issued | shares         3,303,305          
Maximum | 2024 Oaktree Note                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Warrants issued | shares 500,000                  
Maximum | 2020 Oaktree Note                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Warrants issued | shares           0.1        
Chief Executive Officer (Dr. Rosenwald) | Long-Term Incentive Program                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Number of shares, granted | shares   216,465                
Executive Vice President (Mr. Weiss) | Long-Term Incentive Program                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Number of shares, granted | shares     81,286              
Research and development expenses                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Stock-based compensation expense             1,200,000 900,000 2,900,000 2,300,000
General and administrative expenses                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Stock-based compensation expense             5,400,000 3,500,000 13,500,000 11,000,000.0
Stock Options                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Stock options, unrecognized compensation expense             600,000 400,000 $ 600,000 $ 400,000
Share-based compensation, period for recognition of expense                 3 years 3 months 18 days 2 years 8 months 12 days
Restricted Stock Awards and Restricted Stock Units                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Unrecognized compensation expense for awards other than options             $ 6,500,000 $ 13,500,000 $ 6,500,000 $ 13,500,000
Share-based compensation, period for recognition of expense                 1 year 1 year 8 months 12 days
Restricted Stock                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Number of shares, granted | shares                 443,025  
Restricted Stock Units (RSUs)                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Number of shares, granted | shares                 37,500