Condensed Consolidated Statement of Changes in Stockholders' Equity - USD ($) $ in Thousands |
Series A Preferred Stock [Member] |
Common Stock |
Shares Issuable [Member] |
Treasury Stock [Member] |
Paid-In Capital [Member] |
Accumulated Deficit [Member] |
Non-Controlling Interests [Member] |
Total |
Balance at Dec. 31, 2018 |
$ 1
|
$ 58
|
$ 659
|
|
$ 397,408
|
$ (396,274)
|
$ 17,891
|
$ 19,743
|
Balance (in shares) at Dec. 31, 2018 |
1,000,000
|
57,845,447
|
|
|
|
|
|
|
Stock-based compensation expense |
$ 0
|
$ 0
|
0
|
|
6,682
|
|
0
|
6,682
|
Issuance of common stock under ESPP |
$ 0
|
$ 0
|
0
|
|
60
|
|
0
|
60
|
Stock Issued During Period, Shares, Employee Stock Purchase Plans |
0
|
54,221,000
|
|
|
|
|
|
|
Issuance of restricted stock |
$ 0
|
$ 2
|
0
|
|
(2)
|
|
0
|
0
|
Issuance of restricted stock (in shares) |
0
|
1,664,742
|
|
|
|
|
|
|
Issuance of subsidiaries' common shares for license expenses |
$ 0
|
$ 0
|
(164)
|
|
164
|
|
0
|
0
|
Issuance of common stock for at-the-market offering, net |
$ 0
|
$ 8
|
0
|
|
13,859
|
|
0
|
13,867
|
Issuance of common stock for at-the-market offering, net (in shares) |
0
|
7,390,826
|
|
|
|
|
|
|
Preferred A dividends declared and paid |
$ 0
|
$ 0
|
0
|
|
(1,172)
|
|
0
|
(1,172)
|
Partner company's sale of stock, net |
0
|
0
|
0
|
|
60,984
|
|
0
|
60,984
|
Partner company's at-the-market offering, net |
0
|
0
|
0
|
|
26,339
|
|
0
|
26,339
|
Issuance of partner company warrants in conjunction with Horizon Notes |
0
|
0
|
0
|
|
888
|
|
0
|
888
|
Common shares issuable for 2017 Subordinated Note Financing interest expense |
0
|
0
|
490
|
|
0
|
|
0
|
490
|
Common shares issued for 2017 Subordinated Note Financing interest expense |
$ 0
|
$ 0
|
(495)
|
|
979
|
|
0
|
484
|
Common shares issued for 2017 Subordinated Note Financing interest expense (in shares) |
0
|
1,012,646
|
|
|
|
|
|
|
Common shares issuable for 2019 Notes interest expense |
|
|
|
|
|
|
|
(281)
|
Common shares issuable for Opus interest expense |
$ 0
|
$ 0
|
$ 281
|
|
$ 0
|
|
$ 0
|
$ 281
|
Common Shares Issued For Opus Interest Expenses In Shares |
0
|
170,321,000
|
(281,000)
|
|
341,000
|
|
0
|
60,000
|
Non-controlling interest in partner companies |
$ 0
|
$ 0
|
$ 0
|
|
$ (67,235)
|
|
$ 67,235
|
$ 0
|
Deconsolidation of Caelum non-controlling interest |
0
|
0
|
0
|
|
0
|
|
4,849
|
4,849
|
Net loss attributable to non-controlling interest |
0
|
0
|
0
|
|
0
|
|
(32,029)
|
(32,029)
|
Net loss attributable to common stockholders |
0
|
0
|
0
|
|
0
|
(11,706)
|
0
|
(11,706)
|
Issuance of common stock under ESPP |
0
|
0
|
0
|
|
60
|
|
0
|
60
|
Balance at Jun. 30, 2019 |
$ 1
|
$ 68
|
490
|
|
439,295
|
(407,980)
|
57,946
|
89,820
|
Balance (in shares) at Jun. 30, 2019 |
1,000,000,000
|
68,138,203,000
|
|
|
|
|
|
|
Balance at Mar. 31, 2019 |
$ 1
|
$ 63
|
765
|
|
414,870
|
(394,882)
|
29,892
|
50,709
|
Balance (in shares) at Mar. 31, 2019 |
1,000,000,000
|
63,126,521,000
|
|
|
|
|
|
|
Stock-based compensation expense |
|
|
|
|
3,373
|
|
|
3,373
|
Issuance of common stock under ESPP |
|
|
|
|
60
|
|
|
60
|
Stock Issued During Period, Shares, Employee Stock Purchase Plans |
|
54,221,000
|
|
|
|
|
|
|
Issuance of restricted stock (in shares) |
|
55,417,000
|
|
|
|
|
|
|
Issuance of common stock for at-the-market offering, net |
|
$ 5
|
|
|
7,720
|
|
|
7,725
|
Issuance of common stock for at-the-market offering, net (in shares) |
|
4,463,399,000
|
|
|
|
|
|
|
Preferred A dividends declared and paid |
|
|
|
|
(586)
|
|
|
(586)
|
Partner company's offering, net |
|
|
|
|
29,485
|
|
|
29,485
|
Partner company's at-the-market offering, net |
|
|
|
|
25,984
|
|
|
25,984
|
Common shares issuable for 2017 Subordinated Note Financing interest expense |
|
|
490
|
|
|
|
|
490
|
Common shares issued for 2017 Subordinated Note Financing interest expense |
|
|
(484)
|
|
484
|
|
|
|
Common shares issued for 2017 Subordinated Note Financing interest expense (in shares) |
|
268,324,000
|
|
|
|
|
|
|
Common shares issuable for Opus interest expense |
|
|
(281)
|
|
341
|
|
|
60
|
Common Shares Issued For Opus Interest Expenses In Shares |
|
170,321,000
|
|
|
|
|
|
|
Non-controlling interest in partner companies |
|
|
|
|
(42,436)
|
|
42,436
|
|
Net loss attributable to non-controlling interest |
|
|
|
|
|
|
(14,382)
|
(14,382)
|
Net loss attributable to common stockholders |
|
|
|
|
|
(13,098)
|
|
(13,098)
|
Issuance of common stock under ESPP |
|
|
|
|
60
|
|
|
60
|
Balance at Jun. 30, 2019 |
$ 1
|
$ 68
|
490
|
|
439,295
|
(407,980)
|
57,946
|
89,820
|
Balance (in shares) at Jun. 30, 2019 |
1,000,000,000
|
68,138,203,000
|
|
|
|
|
|
|
Balance at Dec. 31, 2019 |
$ 1
|
$ 74
|
500
|
|
461,874
|
(436,234)
|
46,317
|
72,532
|
Balance (in shares) at Dec. 31, 2019 |
1,341,167,000
|
74,027,425,000
|
|
|
|
|
|
|
Stock-based compensation expense |
|
|
|
|
7,148
|
|
|
7,148
|
Issuance of common stock related to equity plans |
|
$ 2
|
|
|
(2)
|
|
|
|
Issuance of common stock related to equity plans (in shares) |
|
2,038,431,000
|
|
|
|
|
|
|
Issuance of common stock under ESPP |
|
|
|
|
90
|
|
|
90
|
Stock Issued During Period, Shares, Employee Stock Purchase Plans |
|
53,268,000
|
|
|
|
|
|
|
Issuance of common stock for at-the-market offering, net |
|
$ 10
|
|
|
22,073
|
|
|
22,083
|
Issuance of common stock for at-the-market offering, net (in shares) |
|
9,314,020,000
|
|
|
|
|
|
|
Preferred A dividends declared and paid |
|
|
|
|
(2,788)
|
|
|
(2,788)
|
Repurchase of Series A preferred stock, net |
|
|
|
$ (70)
|
(2)
|
|
|
(72)
|
Repurchase of Series A preferred stock (in shares) |
(5,000,000)
|
|
|
|
|
|
|
|
Retirement of Series A preferred stock |
|
|
|
70
|
|
|
|
|
Retirement of Series A preferred stock |
|
|
|
|
(70)
|
|
|
|
Issuance of Series A preferred stock for cash, net |
$ 2
|
|
|
|
23,501
|
|
|
23,503
|
Issuance of Series A preferred stock for cash, net (in shares) |
1,357,639,000
|
|
|
|
|
|
|
|
Partner company's offering, net |
|
|
|
|
34,924
|
|
|
34,924
|
Partner company's at-the-market offering, net |
|
|
|
|
10,447
|
|
|
10,447
|
Issuance of partner company's common shares for research and development expenses |
|
|
|
|
21
|
|
|
21
|
Partner company's exercise of warrants for cash |
|
|
|
|
13
|
|
|
13
|
Partner company's ESPP |
|
|
|
|
169
|
|
|
169
|
Common shares issuable for 2017 Subordinated Note Financing interest expense |
|
|
500
|
|
|
|
|
500
|
Common shares issued for 2017 Subordinated Note Financing interest expense |
|
|
(500)
|
|
1,006
|
|
|
506
|
Common shares issued for 2017 Subordinated Note Financing interest expense (in shares) |
|
680,187,000
|
|
|
|
|
|
|
Common shares issuable for 2019 Notes interest expense |
|
|
(313)
|
|
|
|
|
(313)
|
Non-controlling interest in partner companies |
|
|
|
|
(36,911)
|
|
36,911
|
|
Net loss attributable to non-controlling interest |
|
|
|
|
|
|
(26,847)
|
(26,847)
|
Net loss attributable to common stockholders |
|
|
|
|
|
(25,684)
|
|
(25,684)
|
Issuance of common stock under ESPP |
|
|
|
|
90
|
|
|
90
|
Issuance of common stock for research and development expenses |
|
|
|
|
21
|
|
|
21
|
Balance at Jun. 30, 2020 |
$ 3
|
$ 86
|
813
|
|
521,493
|
(461,918)
|
56,381
|
116,858
|
Balance (in shares) at Jun. 30, 2020 |
2,693,806,000
|
86,113,331,000
|
|
|
|
|
|
|
Balance at Mar. 31, 2020 |
$ 2
|
$ 79
|
661
|
(70)
|
485,160
|
(448,604)
|
38,057
|
75,285
|
Balance (in shares) at Mar. 31, 2020 |
2,054,917,000
|
78,572,169,000
|
|
|
|
|
|
|
Stock-based compensation expense |
|
|
|
|
3,748
|
|
|
3,748
|
Issuance of common stock related to equity plans (in shares) |
|
86,024,000
|
|
|
|
|
|
|
Issuance of common stock under ESPP |
|
|
|
|
90
|
|
|
90
|
Stock Issued During Period, Shares, Employee Stock Purchase Plans |
|
53,268,000
|
|
|
|
|
|
|
Issuance of common stock for at-the-market offering, net |
|
$ 7
|
|
|
16,196
|
|
|
16,203
|
Issuance of common stock for at-the-market offering, net (in shares) |
|
6,973,020,000
|
|
|
|
|
|
|
Preferred A dividends declared and paid |
|
|
|
|
(1,581)
|
|
|
(1,581)
|
Retirement of Series A preferred stock |
|
|
|
$ 70
|
|
|
|
|
Retirement of Series A preferred stock |
|
|
|
|
(70)
|
|
|
|
Issuance of Series A preferred stock for cash, net |
$ 1
|
|
|
|
10,435
|
|
|
10,436
|
Issuance of Series A preferred stock for cash, net (in shares) |
638,889,000
|
|
|
|
|
|
|
|
Partner company's offering, net |
|
|
|
|
34,924
|
|
|
34,924
|
Partner company's at-the-market offering, net |
|
|
|
|
5,537
|
|
|
5,537
|
Common shares issuable for 2017 Subordinated Note Financing interest expense |
|
|
500
|
|
|
|
|
500
|
Common shares issued for 2017 Subordinated Note Financing interest expense |
|
|
(506)
|
|
506
|
|
|
|
Common shares issued for 2017 Subordinated Note Financing interest expense (in shares) |
|
428,850,000
|
|
|
|
|
|
|
Non-controlling interest in partner companies |
|
|
|
|
(33,473)
|
|
33,473
|
|
Net loss attributable to non-controlling interest |
|
|
|
|
|
|
(15,149)
|
(15,149)
|
Net loss attributable to common stockholders |
|
|
|
|
|
(13,314)
|
|
(13,314)
|
Issuance of common stock under ESPP |
|
|
|
|
90
|
|
|
90
|
Balance at Jun. 30, 2020 |
$ 3
|
$ 86
|
$ 813
|
|
$ 521,493
|
$ (461,918)
|
$ 56,381
|
$ 116,858
|
Balance (in shares) at Jun. 30, 2020 |
2,693,806,000
|
86,113,331,000
|
|
|
|
|
|
|