Quarterly report pursuant to Section 13 or 15(d)

Debt and Interest (Detail 1)

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Debt and Interest (Detail 1) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Sep. 30, 2015
Sep. 30, 2014
Debt [Line Items]        
Interest     $ 800  
Interest expense related to the Hercules loan $ 350 $ 121 1,033 $ 1,206
IDB Note [Member]        
Debt [Line Items]        
Interest 82 81 235 202
Amortization of fees 1 1 3 3
Interest and Debt Expense, Total 83 82 238 205
NSC Debt [Member]        
Debt [Line Items]        
Interest 208 0 488 0
Amortization of fees 59 0 140 0
Interest and Debt Expense, Total 267 0 628 0
Ovamed Manufacturing Agreement [Member]        
Debt [Line Items]        
Interest 0 39 167 114
Interest and Debt Expense, Total 0 39 167 114
Hercules Debt [Member]        
Debt [Line Items]        
Interest [1] 0 0 0 845
Amortization of fees 0 0 0 42
Interest and Debt Expense, Total $ 0 $ 0 $ 0 $ 887
[1] Interest expense related to the Company’s loan with Hercules was $0.8 million, including $0.4 million related to accretion of the debt discount.