Quarterly report pursuant to Section 13 or 15(d)

Stockholders' Equity (Narrative) (Details)

v3.23.3
Stockholders' Equity (Narrative) (Details)
$ / shares in Units, $ in Thousands
 3 Months Ended 9 Months Ended 12 Months Ended
Aug. 10, 2023
Jan. 01, 2023
shares
Jan. 01, 2022
shares
Aug. 29, 2020
$ / shares
shares
Sep. 30, 2023
USD ($)
shares
Sep. 30, 2022
USD ($)
Sep. 30, 2023
USD ($)
shares
Sep. 30, 2022
USD ($)
Dec. 31, 2022
USD ($)
shares
Jun. 13, 2023
$ / shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Reverse Stock Split ratio 0.0667                  
Common Stock, shares authorized | shares         200,000,000   200,000,000   200,000,000  
Stock-based compensation expense | $         $ 4,377 $ 6,837 $ 13,325 $ 17,481    
Stock options, unrecognized compensation expense | $         400   400      
Exercise price of warrants | $ / shares                   $ 8.136
Change in fair value of Warrant liabilities | $         (4,542)   (10,708)      
Journey                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Stock-based compensation expense | $         $ 558 1,438 $ 2,077 2,985    
Oaktree Note [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Exercise price of warrants | $ / shares       $ 48.00            
Percentage of market price of common stock for additional warrants       95.00%            
Warrants expiration date       Aug. 27, 2030            
2007 and 2013 Stock Incentive Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Stock based compensation, number of shares authorized | shares         1,900,000   1,900,000      
Share based compensation, additional shares authorized | shares             500,000      
Stock based compensation, shares available for issuance | shares         500,000   500,000      
2012 Employee Stock Purchase Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Share based compensation, additional shares authorized | shares             100,000      
Long-term Incentive Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Stock-based compensation expense | $         $ 1,500 1,300 $ 4,400 4,000    
Fair value of stock granted | $             800   $ 1,000  
LTIP, Percentage of outstanding shares   1.00% 1.00%              
Minimum | Oaktree Note [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Warrants issued | shares       100,000            
Chief Executive Officer (Dr. Rosenwald) [Member] | Long-term Incentive Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Number of shares Granted | shares   81,286 81,286              
Executive Vice President (Mr. Weiss) [Member] | Long-term Incentive Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Number of shares Granted | shares   73,532 73,532              
Research and Development Expense [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Stock-based compensation expense | $         900 1,000 2,300 3,600    
General and Administrative Expense [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Stock-based compensation expense | $         3,500 5,800 11,000 13,900    
Interest Expense [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Change in fair value of Warrant liabilities | $             300      
Restricted Stock Awards and Restricted Stock Units [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Unrecognized compensation expense for awards other than options | $         $ 13,500 $ 22,900 $ 13,500 $ 22,900    
Share-based compensation, period for recognition of expense             1 year 8 months 12 days 2 years    
Restricted Stock [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Number of shares Granted | shares             171,905      
Restricted Stock Units (RSUs) [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Number of shares Granted | shares             12,666