United States securities and exchange commission logo June 24, 2024 Lindsay A. Rosenwald Chief Executive Officer Fortress Biotech, Inc. 1111 Kane Concourse, Suite 301 Bay Harbor Islands, FL 33154 Re: Fortress Biotech, Inc. Registration Statement on Form S-3 Filed June 20, 2024 File No. 333-280342 Dear Lindsay A. Rosenwald: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Tyler Howes at 202-551-3370 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: David Wolpa, Esq.