United States securities and exchange commission logo May 24, 2024 Lindsay Rosenwald Chief Executive Officer Fortress Biotech, Inc. 1111 Kane Concourse, Suite 301 Bay Harbor Islands, FL 33154 Re: Fortress Biotech, Inc. Registration Statement on Form S-3 Filed May 17, 2024 File No. 333-279516 Dear Lindsay Rosenwald: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Lauren Hamill at 303-844-1008 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: David Wolpa